This publication reports on a pilot program on Acquired Immune Deficiency Syndrome (AIDS) and life skills training implemented in 12 schools in Pretoria, Laudium, Cape Town, and Soweto (South Africa). Data were collected through pre- and post-questionnaires and focus group interviews. The purpose of the program was to provide adolescents with accurate information on which decisions about AIDS prevention behavior and tolerance towards people infected with the Human Immunodeficiency Virus (HIV) would be based. The program had 10 modules, each with specific teaching objectives; suggested teaching methods, teaching aids, and learning activities; and suggestions for additional reading. The modules addressed puberty and adolescence, relationships (e.g., peer, family, opposite sex), love, human sexuality, decision making, sexually transmitted diseases (STDs), and HIV/AIDS. Findings indicated that students showed a general improvement in AIDS-related knowledge topics as well as more positive perceptions of condom use, and more realistic perceptions regarding susceptibility, and the seriousness and outcomes of HIV/AIDS. There was also an increased perception of peer pressure to engage in sexual activity. A number of recommendations regarding the context of the program are outlined, first in terms of various survey fields and second with regard to the improvement of the program modules. Appendices include: descriptions of statistical techniques and survey fields; anova analysis; pre- and post-test mean scores; percentages on specific items; and prescribed reading materials. (Contains 36 references.) (ND)