This Acquired Immune Deficiency Syndrome (AIDS) Curriculum was developed for intermediate elementary (5th, 6th, and 7th grade) students. It is an integrated unit that encompasses health, science, social studies, math, and language arts. The curriculum is comprised of nine class activities designed to meet the following objectives: (1) to determine what students know about AIDS in such a way that students will provide honest information; (2) to provide information about diseases and disease-causing organisms; (3) to learn how the human immune system operates; (4) to gain accurate information about AIDS; (5) to gain compassion for people with AIDS; (6) to gain information about AIDS transmission; (7) to gain accurate information about the distribution of AIDS in the United States, to learn how to process data from the information given, and to learn about AIDS in the student's state; (8) to apply information learned about AIDS to a situation and to show compassion for people with AIDS by writing about a situation; and (9) to learn how to make good decisions by exploring alternatives and consequences and to apply decision-making to a situation where AIDS could be transmitted. The manual contains reproducible student handouts, transparency masters, a sample parent letter, and a cognitive test which assesses student knowledge of key facts about AIDS. (LL)