We developed labs on the evolution of antibiotic resistance to assess the costs and benefits of replacing traditional laboratory exercises in an introductory biology course for majors with a course-based undergraduate research experience (CURE). To assess whether participating in the CURE imposed a cost in terms of exam performance, we implemented…

Students possess informal, intuitive ways of reasoning about the world, including biological phenomena. Although useful in some cases, intuitive reasoning can also lead to the development of scientifically inaccurate ideas that conflict with central concepts taught in formal biology education settings, including evolution. Using antibiotic…

The current COVID-19 pandemic shows how little many people know about viruses. Yet apart from COVID-19, the world has observed epidemic spread of another SARS virus, of the Ebola virus, and of the Zika virus during the last two decades. The human immunodeficiency virus (HIV) is still one of the most dangerous viruses worldwide. Some types of the…

Tuberculosis (TB) continues to be a serious global health problem, resulting in >1.4 million deaths each year. Of increasing concern is the evolution of antibiotic resistant strains of the bacterium that causes TB. Using this real-world scenario, we created a 90-minute activity for high school or undergraduate students to use online…

The evolution of resistance to antibiotics provides a timely and relevant topic for teaching undergraduate students evolutionary biology. Here, we present a module incorporating modified sequencing data from eight antibiotic resistant pathogen outbreaks in hospital settings with bioinformatics and phylogenetic analyses. This module uses whole…

Antibiotic resistance is typically used to justify education about evolution, as evolutionary reasoning improves our understanding of causes of resistance and possible countermeasures. It has also been promoted as a useful context for teaching natural selection, because its potency as a selection factor, in combination with the very short…

Describes (in separate articles) 20 developments in science, technology, and medicine that were made during the twentieth century and had significant impact on society. They include discoveries related to intelligence tests, plastics, aviation, antibiotics, genetics, evolution, birth control, computers, transistors, DNA, lasers, statistics,…

Plasmids exist in bacteria and are small, extrachromosomal pieces of DNA that often encode accessory genes such as antibiotic resistance genes. They are largely responsible for spreading antibiotic resistance genes through bacterial populations via their ability to conjugate into different bacterial hosts or species. In environments without…

Natural selection is a central concept throughout biology; however, it is a process frequently misunderstood. Bacterial resistance to antibiotic medications provides a contextual example of the relevance of evolutionary theory and is also commonly misunderstood. While research has shed light on student misconceptions of natural selection, minimal…

The present study explores the extent and precision of evolutionary explanations for antibiotic resistance in communication directed toward the Swedish public. Bacterial resistance develops through evolutionary mechanisms and knowledge of these helps to explain causes underlying the growing prevalence of resistant strains, as well as important…

Evolution is typically measured as a change in allele or genotype frequencies over one or more generations. Consequently, evolution is difficult to show experimentally in a semester-long lab course because most organisms have longer generation times than 15 weeks. In this article, the authors present an experiment to demonstrate and study…

Biology teachers are accustomed to engaging individuals who do not accept biological evolution. Denial of evolution ranges from ignorance of the evidence to outright denial or distortion of data. The list of science denial topics has grown alarmingly over the years to include: HIV as the cause of AIDS, exaggeration of the health and environmental…

Antibiotic resistance, genetically modified produce, avian flu, and invasive species persistence are just a few scientific issues pulled from the headlines that affect society on a daily basis. Understanding these issues requires knowledge of evolutionary processes. Educating students about evolution may never have been as necessary as it is…

The goal of the work reported here was to help students expand their understanding of antibiotic resistance, the Central Dogma, and evolution. We developed a unit entitled "Ciprofloxacin Resistance in "Neisseria gonorrhoeae,"" which was constructed according to the principles of scientific teaching by a team of graduate students, science faculty,…

Horizontal gene transfer, the exchange of genetic material between bacteria, is a potentially important factor in the degradation of synthetic compounds introduced to the environment and in the acquisition of other characteristics including antibiotic resistance. This game-based activity illustrates the role of horizontal gene transfer in the…