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Klinke, Sebastián; Rinaldi, Jimena; Goldbaum, Fernando A.; Suarez, Sebastián; Otero, Lisandro H. – Biochemistry and Molecular Biology Education, 2019
X-ray crystallography provides structural information of molecules at the atomic level, being a central technique at the forefront of science and technology. However, crystallography teaching is not usually implemented in biochemistry lab classes due to its complex execution by nonexpert users. Here, we report the basic step-by-step workflow…
Descriptors: Molecular Biology, Biochemistry, Science Laboratories, Laboratory Experiments
Poeylaut-Palena, Andres, A.; de los Angeles Laborde, Maria – Biochemistry and Molecular Biology Education, 2013
A learning module for molecular level analysis of protein structure and ligand/drug interaction through the visualization of X-ray diffraction is presented. Using DeepView as molecular model visualization software, students learn about the general concepts of protein structure. This Biochemistry classroom exercise is designed to be carried out by…
Descriptors: Introductory Courses, Class Activities, Molecular Structure, Science Activities
Goodsell, David S. – Biochemistry and Molecular Biology Education, 2012
Data from electron microscopy, X-ray crystallography, and biophysical analysis are used to create illustrations of viruses in their cellular context. This report describes the scientific data and artistic methods used to create three illustrations: a depiction of the poliovirus lifecycle, budding of influenza virus from a cell surface, and a…
Descriptors: Molecular Biology, Microbiology, Science Instruction, College Science
Horowitz, Scott; Koldewey, Philipp; Bardwell, James C. – Biochemistry and Molecular Biology Education, 2014
Recently, 57 undergraduate students at the University of Michigan were assigned the task of solving a crystal structure, given only the electron density map of a 1.3 Å crystal structure from the electron density server, and the position of the N-terminal amino acid. To test their knowledge of amino acid chemistry, the students were not given the…
Descriptors: Undergraduate Students, Biochemistry, Assignments, Science Activities