This article explores the opportunity to create spaces within the family, school, and community that specifically promote the well-being of transgender adolescents and young adults. When social contexts are supportive, transgender youth report significantly less risk. Supportive home and school environments have been linked to better outcomes among transgender youth. In some cases support via youth organizations can mitigate the influences of a negative home or school environment through direct services to youth and their families, outreach to community allies, and advocacy in local policies. The article concludes with recommendations for youth organizations to be inclusive and supportive of all gender identities and expressions. (Contains 1 table and 2 boxes.)