Depression has been extensively studied for mothers but not for fathers. This study examines the sociodemographic correlates of symptoms of depression and how depression is associated with father involvement using the Composite International Diagnostic Interview-Short Form (CIDI-SF) for major depression. The study uses a sample of 2,139 resident fathers in the Fragile Families and Child Wellbeing 12-Month Father Survey. Results indicate that symptoms of major depression differ by race, marital status, and employment status but not by age and educational status. Major depression also differs significantly based on drug and alcohol use and criminal justice experience. Results of ordinary least squares regression models indicate that major depression is negatively associated with father-child activities (engagement), positively associated with paternal aggravation/stress in parenting, and negatively associated with both the quality of the mother-father relationship and coparental relationship supportiveness. Findings are important for identifying fathers for whom interventions would be valuable. (Contains 3 tables and 2 notes.)