Across the nation and for a very long time, campuses and students have been plagued by drug and alcohol abuse. And it seems that many of our efforts to address that abuse, while necessary, have been woefully insufficient to the task. This article describes the nature and significance of the problem, examines current strategies for addressing it, suggests what we might do to be more effective in our efforts to eradicate it, and then lists some common features that new or renewed efforts to reduce substance abuse should share.