This paper explores the factors that contribute to the development of positive stress and distress in teachers within secondary schools in England. It draws on narrative interviews undertaken with 12 mathematics and science teachers in six schools and focuses on three of these teachers to explore issues in more depth. The findings demonstrate that the use by teachers of appropriate coping mechanisms, e.g. actively seeking out preferable alternatives, and access to professional and personal support, with the right frame of mind, namely, seeing stressors as capable of being overcome, can produce desirable consequences for the teachers through their use of stress in a positive, healthy manner and lessen the likelihood of negative long-term effects associated with distress.