This paper focuses on two research-based frameworks that inform the design of instruction and promote student success in accelerated, developmental mathematics pathways. These are Learning Opportunities--productive struggle on challenging and relevant tasks, deliberate practice, and explicit connections, and Productive Persistence--promoting students' academic and social mindsets, and good strategies. These frameworks are the foundations of the highly successful Carnegie Pathways (Statway and Quantway), two distinct pathways that take students who place into developmental mathematics through college-level mathematics in one year. In this paper, we describe these research-based frameworks and discuss examples of high impact practices derived from them.