Fluency, the subjective experience of ease associated with information processing, has been shown to affect a host of judgments. Previous research has typically focused on specific factors that affect the use of a single, specific fluency source. In the present study we examine how cognitive mindsets, or processing modes, moderate fluency emanating from two simultaneous sources of fluency. As a cognitive mindset manipulation, participants performed Jacoby's process dissociation paradigm. Subsequently, participants engaged in a metamemory task that incorporates (and can separately measure the influence of) two simultaneous sources of fluency: familiarity and accessibility. Our results confirmed that our content-unrelated mindset procedure had affected the use of fluency. Moreover, the use of both fluency sources was attenuated, demonstrating the generality of the effect. The findings highlight the causal dependency of fluency on a complex, cognitively-rich environment. (Contains 1 figure.)