Self-esteem is vital to a law-abiding lifestyle and serves to promote successful rehabilitative and reintegrative outcomes, particularly for female offenders often plagued by low levels of self-worth. Prison-based program administrators have the opportunity to achieve their intended programmatic goals while offenders are incarcerated, in addition to achieving unintended complementary effects, such as the enhancement of inmate self-esteem, which is essential for rehabilitative success. This study analyzed levels of self-esteem among 49 female prisoners that worked in two HIV prison-based peer programs (ACE and CARE) as peer educators during their incarceration. Overall, self-esteem among this group was quite high.