This handbook provides information on establishing and running learning centers in an elementary school classroom. A learning center is a station containing instruction and materials for one particular project. Every center should include multimedia and manipulative materials that support the topic or skill that is being focused upon. Students use a learning center for self-selected activities, while teachers find it useful as an area for followup lessons or small group instruction. Diagrams are presented showing possible physical arrangements for one or more learning centers in a classroom. Practical suggestions are given for using materials to enhance these areas along with strategies for organizing and managing the centers. Learning center activities are outlined, and the purpose and materials for each activity are described. A bibliography lists available commercial materials that contain activities and ideas for the development of learning centers. (JD)