Environments in which learning involves coordinating multiple external representations (MERs) can productively support learners in making sense of complex models and relationships. Educational digital games provide an increasing popular medium for engaging students in manipulating and exploring such models and relationships. This article applies cognitive science research on MERs to a range of popular educational and recreational games that focus on the interpretation and manipulation of models. We leverage the literatures on embodied cognition, adaptive scaffolding, science education, and dynamic visualizations to address the challenges, trade-offs, and questions highlighted by the research. We apply these research-derived design considerations to analyze (a) the extent and forms through which the design considerations are reflected in the design of the games, (b) the implications for designing effective model-based games for learning, and (c) the implications for future research on MERs.