Presents data on release of renin during direct and indirect stimulation of renal nerves. Conclusions show that renin release is influenced by change in activity of carotid and cardiopulmonary baroreceptor systems, and excitation of discrete areas of brain and hypothalamus by changes in renal sympathetic nerve. (Author/SA)

Given the rise in chronic kidney disease (CKD) in both children and adults, CKD has recently been targeted as a public health priority. Childhood onset kidney disease is generally a noncurable and progressive condition that leads to kidney failure by early adulthood. Fortunately, improved identification of kidney problems allows for early…

Stimulus-secretion coupling (SSC) in endocrine cells remains underappreciated as a subject for the study/teaching of general physiology. In the present article, we review key new electrophysiological, electrochemical, and fluorescence optical techniques for the study of exocytosis in single cells that have made this a fertile area for recent…

Examined were eight patients with cerebro-hepato-renal syndrome of Zellweger (associated with severe cerebral dysfunction, hypotonia and unusual appearance). (CL)

Obstructive sleep apnea (OSA) is a common disorder of upper airway obstruction during sleep. The effects of intermittent upper airway obstruction include alveolar hypoventilation, altered arterial blood gases and acid-base status, and stimulation of the arterial chemoreceptors, which leads to frequent arousals. These arousals disturb sleep…

Studied were three unrelated infants with distal renal tubular acidosis (a condition characterized by an inability to acidify the urine to minimal pH levels resulting in the loss of bicarbonates). (DB)

A computer-assisted instruction (CAI) unit was designed to teach renal diet therapy. Utilizing this unit, differences in performance and attitudes between traditionally taught and CAI taught students (N=34), and differences in achievement between students in two nutrition fields were assessed. (DS)

This article reviews studies focusing on the psychological aspects and problems of renal disease. Findings suggest that disabled individuals do not become emotionally disturbed by their disability but by beliefs about their disability, opinions about the treatment, and events subsequent to their disability. Use of rational counseling techniques is…

Aquatic therapy is the use of the properties of water for the therapeutic benefit of people of all ages and abilities. This article illustrates how people with disabilities may maximize the benefits of activities in water, including individual and group work and swimming. The overall aim is to encourage family activity and social interaction. The…

More children and adolescents who have chronic illnesses are being included in regular education classrooms today than ever before. However, teachers may not feel confident about being able to meet these children's educational, social, or emotional needs in the classroom. School psychologists are able to assess children's functioning in these…

Reviews the important relationship between end-stage renal disease (ESRD) and hypertension for African Americans; and considers issues associated with ESRD and the subsequent need for kidney transplants, including organ availability. Individual and societal implications of these diseases are discussed. (SLD)

Reviews factors involved in the rapid growth of medical ethics. Renal dialysis is discussed as an example of a problem in this applied field of ethics. (CS)

Provides background information, defining areas within organ systems where physiological waterfalls exist. Describes pressure-flow relationships of elastic tubes (blood vessels, airways, renal tubules, various ducts). (CS)

Included in the review are a description of the anatomic and functional development of the human kidney, a comparison of the renal physiology of the infant and adult, and a discussion of the pediatric clinical pharmacology of the most commonly used diuretic agents. (DB)