This study examined lecturers' perception of research activities for knowledge production in universities in Cross River State, Nigeria. Two hypotheses were isolated to give direction to this investigation. 240 university lecturers were sampled from a population of 1,868 from the two universities in Cross River State, using stratified random sampling technique. Results revealed that lecturers' perception of research activities has a significant relationship with knowledge production. Lecturers' perception of research activities for knowledge production is not significantly influenced by university type. It was recommended that government should support research activities in universities through funding to promote knowledge production which pays them back in terms of contributing to the development of the economy, political and social systems.