Although counseling psychology has discussed vocational issues, health concerns, diversity, and social justice, discussion of these topics has typically been narrowly focused. This article uses the example of persons with HIV (PWHIV) to demonstrate how these areas can be intertwined. The counseling psychology literature is also examined to determine the degree to which direction has been provided regarding clients facing health concerns, disabilities, confusion regarding career issues, or possible discrimination. Because HIV is now considered to be a chronic illness for many people, there is an increased likelihood that PWHIV will be faced with employment issues, as well as significant barriers to beginning work, returning to work, or keeping a job. After highlighting characteristics of PWHIV, we review the degree to which the vocational literature addresses the needs and issues of PWHIV. We also examine the role of social justice in relation to PWHIV who are considering work.