Bruce Perry's "Neurosequential Model of Therapeutics" (NMT) has great potential for enriching how children are cared for in families and in the social institutions charged with treating emerging disorders in young children. The NMT also suggests that many, if not most, currently used interventions seem pale and destined to have little or no effect on maturational outcomes because of their ignorance of target areas in the brain. Clinicians and child protective service practitioners need to have a clear understanding of how the brain and environment interact to produce thinking, feeling and behaving. Clinicians must learn how to think neurodevelopmentally throughout assessment and treatment. This is different from seeing evidence-based practices as manualizable stepwise components that can be blindly followed in the clinical setting. NMT requires a far more sophisticated education of clinical professionals during their graduate exposure instead of depending on episodic training on packaged evidence-based practices.