Purpose: Little is known about the employment-related decisions made by people with Parkinson's disease (PD). This study investigated the extent to which individuals diagnosed with PD would prefer to continue working or, if currently unemployed, reenter the workforce. Method: This quantitative survey research design consisted of a purposive sample…

Purpose: Reduced intensity is a hallmark of speech production in Parkinson's disease (PD). Previous work has examined the perception of intensity in PD to explain these speech deficits. This study reports loudness ratings of pure tones by individuals with PD and controls, all with normal thresholds for older adults. Method: Twenty individuals with…

Purpose: Auditory training has been shown to reduce rater variability in perceptual voice assessment. Because rater variability is also a central issue in the auditory-perceptual assessment of dysarthria, this study sought to determine if training produces a meaningful change in rater reliability, criterion validity, and scaling magnitude of four…

Purpose: The purpose of the current study was to characterize clear speech production for speakers with and without Parkinson disease (PD) using several measures of working vowel space computed from frequently sampled formant trajectories. Method: The 1st 2 formant frequencies were tracked for a reading passage that was produced using habitual and…

Purpose: The effects of neurological diseases on the auditory system have been a notable issue for investigators because the auditory pathway is closely associated with neural systems. The purposes of this study are to evaluate the efferent auditory system function and hearing quality in Parkinson's disease (PD) and to compare the findings with…

Purpose: We recently demonstrated that individuals with Parkinson's disease (PD) respond differentially to specific altered auditory feedback parameters during speech production. Participants with PD respond more robustly to pitch and less robustly to formant manipulations compared to control participants. In this study, we investigated whether…

Several attempts have been made previously to provide a biological grounding for cognitive architectures by relating their components to the computations of specific brain circuits. Often, the architecture's action selection system is identified with the basal ganglia. However, this identification overlooks one of the most important features of…

Enzymes are widely applied in different industries, like pharmaceutical, food, biofuel, and waste valorization. However, the enzyme operating conditions are very limited. So, in most industrial processes, enzymes are not efficient, due to the use of harsh conditions, like organic solvents, extreme pH, and temperature. Immobilization arises as a…

Purpose: Alterations in primary auditory functioning have been reported in patients with Parkinson's disease (PD). Despite the current findings, the pathophysiological mechanisms underlying these alterations remain unclear, and the effect of dopaminergic medication on auditory functioning in PD has been explored insufficiently. Therefore, this…

Objective: The Internet and other electronic media may provide one part of a solution for reducing disparities in the availability of medical services. From a patient-centred perspective, an individual with a chronic, degenerative condition may ask what information is available that I can use to manage changes in my functional capacity over time,…

Purpose: This study evaluated the accuracy of respiratory calibration methods for estimating lung volume during speech breathing. Method: Respiratory kinematic data were acquired via inductance plethysmography in 32 young adults, 22 older adults, and 13 older adults with Parkinson's disease (PD). Raw rib cage (RC) and abdomen (AB) signals (V) were…

Purpose: The aim of the current investigation was to examine speech motor sequence learning in neurologically healthy younger adults, neurologically healthy older adults, and individuals with Parkinson disease (PD) over a 2-day period. Method: A sequential nonword repetition task was used to examine learning over 2 days. Participants practiced a…

Purpose: Individuals with Parkinson's disease (PD) demonstrate language- and emotion-related impairments; however, emotional language production has received little attention within the literature despite the fact that deficits could significantly impact one's daily interactions with loved ones and others. Multitasking (i.e., dual tasking),…

Background: Parkinson's disease (PD) is a movement disorder with no cure. Symptoms related to PD can be managed through physical activity (PA). However, individuals with PD tend to be sedentary. Purpose: The purpose of this study was to identify the perceived constraints and facilitators to PA in each stage of behavioral change for individuals…

Levodopa-induced dyskinesia is a major complication of long-term dopamine replacement therapy for Parkinson's disease that becomes increasingly problematic in advanced Parkinson's disease. Although the cause of levodopa-induced dyskinesias is still unclear, recent work in animal models of the corticostriatal system has suggested that…