The authors describe the construction and use of tactile models for demonstrating intermolecular forces. These models are composed of inexpensive materials and can be used in college chemistry classrooms of varying levels including general and organic chemistry. The models were designed to be paired with an accompanying activity to encourage…

Organic chemistry students struggle with understanding the energetics of chemical reactions. Reaction coordinate diagrams are one tool that is widely used in organic chemistry classrooms to assist students with visualizing and explaining the energy changes that take place throughout a reaction. Thirty-six students enrolled in organic chemistry II…

Collaborative experiences have been widely integrated into the classroom and laboratory, with goals to build time management, communication, and team-working skills. Most reported laboratory collaborations occur between students within the same lab section, which could limit the potential benefits of these experiences. Presented herein is an…

Curriculum-based undergraduate research experiences (CUREs) have been shown to increase student retention in STEM fields and are starting to become more widely adopted in chemistry curricula. Here we describe a 10-week CURE that is suitable for a second-semester organic chemistry laboratory course. Students synthesize small molecules and use…

New Inquiry-Based Learning (NIBL) was developed to improve students' multiple higher-order thinking skills (M-HOTS), such as thinking critically, analytically, creatively, and practically (CACP). This study aimed to examine the increase of students' M-HOTS ability, their perceptions of the NIBL model, and the contribution of the NIBL model to the…

How well does the undergraduate organic chemistry laboratory curriculum prepare students for academic research, or for a bench job in industry? Running experiments that are more representative of research chemistry has the potential to better equip students for working in a research laboratory, while at the same time giving them insight into a…

Acquiring conceptual understanding seems to be one of the main challenges students face when studying organic chemistry. Traditionally, organic chemistry presents an extensive variety of chemical transformations, which often lead students to recall an organic transformation rather than apply conceptual knowledge. Strong surface level focus and…

We designed the current gamification strategy for an undergraduate introductory organic chemistry course to enhance the student engagement. We implemented it in two classes from the Pharmacy and Chemistry courses using several gaming elements: attendance, punctuality, game-based applications, board games, knowledge tournament, video classes, and…

Despite the importance of organic chemistry to human health and quality of life, very few outreach programs have been successful in communicating this message. This contributes to negative public perceptions of organic chemistry and obscures the enormous advances in quality of life engendered by organic synthesis. New chemical outreach programs…

A significant number of instructors, researchers and students have claimed that chemistry is a challenging subject to teach and learn at all education levels. Its main learning difficulties are in line with certain sights of its phenomena that are abstract, and some chemistry teachers do not specify what to be learned and assessed in chemistry…

Rapid advances in the quality and accessibility of immersive virtual reality (IVR) have brought about intense interest in applications of the technology within higher education, including STEM (science, technology, engineering, mathematics) teaching and learning. However, evidence is mixed on the effectiveness of IVR for STEM teaching and…

Research in organic chemistry education has revealed that students often rely on rote memorization when learning mechanisms. Not much is known about student productive resources for causal reasoning. To investigate incipient stages of student causal reasoning about single mechanistic steps of organic reactions, we developed a theoretical framework…

Williamson ether experiments are commonly performed by students in undergraduate organic chemistry instructional laboratory courses. In this multioutcome experiment, students were provided 4-bromophenol and one of three alkyl halides: 1-bromopentane, 1-bromobutane, or 1-bromo-3-methylbutane. The alkyl halides served as the unknown component of the…

The advanced organic chemistry experiments describe the preparation of fused six-membered lactams to isoxazole and isoxazoline by employing Ugi four-component reaction (U-4CR) and intramolecular nitrile oxide cyclization (INOC) synthetic sequence. The experiments were carried out in 28 h (overnight for U-4CR) and 2 h (for INOC) using commercially…

Introductory organic chemistry laboratory is often a difficult course for students in terms of translating the structural information and reactivity learned in lecture to the practical applications found in the laboratory. These concepts are even more difficult when presented through distance learning when a student cannot get hands-on experience.…