Using 5 divergent thinking indices of the Torrance Tests of Creative Thinking and the Myers-Briggs Type Indicator, this study examined the creative profiles of 236 adult professionals and relationships between their creative characteristics and personality types. All these adults were in their middle or late stage of professional development in business, public service, journalism, or a similar profession. Distinctive profiles of creative and personality characteristics were found as a function of the domain. For example, the adults in business, journalism, and law had strength in fluency and a weakness in resistance to premature closure; those in medicine, and research and education showed strength in originality and a weakness in abstractness of titles. Those in business were mostly either an ESTJ or ISTJ type had lower levels of creativity than other professionals. Across the domains, the adults preferring intuition in perceiving information had higher creative potential than those preferring sensing. Domains were significant predictors of most of the tested creativity, even over and above the personality types. Overall, this study supported that creative potential, personality types, and domains are intertwined although further explorations are needed to identify causality among them.