ERIC Number: EJ820309
Record Type: Journal
Publication Date: 2006-Nov
Pages: 3
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-0021-9584
EISSN: N/A
Microwave-Mediated Synthesis of Lophine: Developing a Mechanism to Explain a Product
Crouch, R. David; Howard, Jessica L.; Zile, Jennifer L.; Barker, Kathryn H.
Journal of Chemical Education, v83 n11 p1658-1660 Nov 2006
The microwave-mediated preparation of lophine (2,4,5-triphenylimidazole) is described. This experiment allows for an introduction to the emerging technology of microwave-assisted organic synthesis while providing an opportunity for students to employ the principles of carbonyl chemistry in devising a mechanism to explain the formation of the product. When combined with previously published methods for heterocycle synthesis, this experiment offers an example of the advantages of microwave-assisted synthesis. (Contains 2 schemes.)
Descriptors: Organic Chemistry, Scientific Principles, Science Instruction, Laboratory Experiments, Molecular Structure, Kinetics, College Science, Undergraduate Students, Undergraduate Study
Division of Chemical Education of the American Chemical Society. Subscription Department, P.O. Box 1267, Bellmawr, NJ 08099-1267. Tel: 800-691-9846; Tel: 856-931-5825; Fax: 856-931-4115; e-mail: jchemed@egpp.com; Web site: http://www.jce.divched.org
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education; Postsecondary Education
Audience: Teachers
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A