Refereed journals in science and medicine are the gatekeepers and repositories of knowledge in their respective fields. Research reported in peer-reviewed journals builds professional careers, determines which drugs and medical devices are licensed, influences what medical treatments become standards of care, and establishes the veracity of scientific theories. Maintaining the reliability, integrity, and objectivity of journal content is paramount, particularly in an era of increasingly common university-industry partnerships. These relatively new university-industry partnerships, largely fostered by federal policies put in place in the early 1980s, have required government funding agencies and journal editors alike to rethink how to ensure publication integrity. Yet despite the best efforts of editors to set standards of research integrity, the escalation in conflicts of interest in academic science and medicine that has occurred over the past three decades has cast a shadow over many publications. Most scientific and medical journals now have conflict-of-interest policies in place, but disclosure alone does not ensure scientific integrity. In this article, the author talks about disclosure of conflicts of interest as a first step toward scientific integrity.