Immigrants from Latin America are increasingly settling in rural U.S. communities that welcome them as workers but are often unprepared to address their needs and promote their well-being. Building on recent descriptive studies, we examined factors associated with individual and family well-being in a sample of 112 immigrant Latina mothers (mean age 34.5 years, 93% Mexican) who completed in-person interviews. Mothers who reported a more negative community climate reported lower levels of individual and family well-being (life satisfaction, financial well-being, and food security). Composite measures of economic and social capital were positively related to family well-being; unexpectedly, mothers with higher levels of human capital reported lower levels of life satisfaction. Discussion focuses on implications of results for future research, theory-building, and practice. (Contains 3 tables.)