This essay enacts a philosophy of science education inspired by Gilles Deleuze and Felix Guattari's figurations of rhizomatic and nomadic thought. It imagines rhizomes shaking the tree of modern Western science and science education by destabilising arborescent conceptions of knowledge as hierarchically articulated branches of a central stem or trunk rooted in firm foundations, and explores how becoming nomadic might liberate science educators from the sedentary judgmental positions that serve as the nodal points of Western academic science education theorising. This is demonstrated by commencing two rhizomatic textual assemblages that generate questions, provocations and challenges to dominant discourses and assumptions of contemporary science education. The first of these addresses cultural representations of Sir Isaac Newton and the second makes multiple, hybrid connections among the parasites, mosquitoes, humans, technologies and socio-technical relations signified by malaria.