The use of virtual learning environments (VLEs) has become more common and educators recognized the potential of VLEs as educational environments. The learning community in VLEs can be a mixture of people from all over the world with different cultural backgrounds. However, despite many studies about the use of virtual environments for learning, there has been little research on the perspectives of both instructors and students from different cultural backgrounds toward using a VLE. Thus, to gain insight into both instructors' and students' perspectives with different cultural backgrounds toward using a VLE, this paper conducted a qualitative exploratory case study. For more interactive learning, the VLE of the study was designed in Second Life which is one of the 3D VLEs and equipped with screen sharing software. In addition, one facilitator provided the technical and language translation support throughout the research process. Then, this paper also endeavored to determine educational implications of this new approach based on its findings.