A key goal of science and engineering education is to provide opportunities for people to access, interpret, and make use of science and engineering to address practical human needs. Most education research, however, focuses on how best to prepare students in schools to participate in forms of science and engineering practices that resemble those of disciplinary experts. In this paper, I argue that education research is needed that focuses on how people use science and engineering in social practices as part of collective efforts to transform cultural and economic production. Drawing on social practice theory, I argue that learning inheres in such activities, not only because people access and make use of science knowledge and develop repertoires for participating in science and engineering practices, but also because participation in such activities transforms the ways that people imagine themselves and expands their possibilities for action. Research can inform and support these efforts, both directly and indirectly, by giving an account of the conditions for science and engineering learning and by diagnosing inequities in access to science and engineering for addressing pressing human needs.