In large classes, students' feelings of anonymity and interpersonal distance from the instructor can be particularly detrimental to those who struggle with course material. We tested a simple method for connecting with struggling students to improve their performance. We randomly divided students who scored 75% or lower on the first exam into 2 groups. Students in one group received a personalized e-mail message expressing our concern and providing information about course resources. Students in the other group served as a no-e-mail control. Those who received the message performed better on the second exam than those who did not. We discuss possible explanations for our findings and question whether multiple e-mails might enhance performance more consistently. (Contains 1 figure, 5 footnotes and 1 note.)