The authors examined the roles of reasons for living and coping in protecting against suicidal behaviors among 361 Black college students. Results of a path analysis revealed that reasons for living mediated against suicidal ideation through an inverse effect on depression. Results also indicated that greater use of emotion-oriented coping may lead to suicidal ideation through increased depression and decreased reasons for living, whereas avoidance-oriented coping protected against suicide. Implications for these results are further discussed. (Contains 2 tables and 2 figures.)