The transition to parenthood is a time of stress for many couples. Most research on the transition to parenthood has been conducted with middle-class, heterosexual couples. The current study uses multilevel modeling to examine predictors of change in relationship quality (love and conflict) during the transition to parenthood in 29 lesbian couples. Predictors included personality variables, work context variables, social context variables, and couple characteristics. Results suggest that personality and couple characteristics were important predictors of change in love, whereas personality and expected social support were salient predictors of change in conflict. The importance of research on this key life transition for lesbian couples is discussed.