In this article, the authors describe how an existing partnership between two communities, one in eastern Iowa and one in Mexico, was turned into a cross-disciplinary and international service learning course for students in the University of Iowa Colleges of Engineering, Pharmacy, and Liberal Arts and Sciences. The projects that students worked on through the service-learning component of their university courses were directly related to the development needs the Mexican community had identified. The authors discuss the benefits of the initiative for both communities and make suggestions for how it could be enhanced in the future.