Biology, physiology, and allied health biochemistry textbooks cover metabolic pathways such as glycolysis; however, most do not include much discussion of how these pathways are regulated within the cell. Because the details of these complex regulatory processes can be difficult for students to learn, we have developed a robust teaching analogy that compares the glycolytic synthesis of ATP to the generation of electrical power. Analogies comparing glucose catabolism to coupled industrial engines (1) and to family finances (2) have been published, but these do not include any notion of regulation. A detailed analogy comparing an enzyme to a butcher (5) deals with enzyme structure, mechanism, and regulation, but only for a single enzyme. Thus we feel that our glycolysis/ power generation analogy, which envisions the regulation of an entire metabolic pathway, is uniquely useful. In our scheme, we identify three key regulatory enzymes in glycolysis: hexokinase, phosphofructokinase, and pyruvate kinase, along with some of their activators and inhibitors. Our analogy compares three key parts of the electric power generation system with these three major regulatory enzymes in the glycolytic pathway. The target audience for this analogy is lower-division undergraduates studying metabolism in courses such as introductory biology, physiology (especially human physiology), introductory biochemistry, and nursing/allied health courses.