The aim of this study was to investigate the feasibility of the Mindfulness Art Therapy Short Version for Japanese patients with advanced cancer. Patients learned mindfulness practices and then made art to express their feelings in the first session. After receiving instruction on practicing mindfulness 2 weeks later, they participated in a second session. The Profile of Mood States and Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being Scale were administered before the first session and after the second. Results suggest that this intervention may be effective for increasing vigor and reducing fatigue; for reducing tension, depression, and confusion; and for improving overall mood.