Examining an aggregated sample (N=8800) of residents who responded to one of 16 surveys undertaken in Prince George, British Columbia in the period from November 1997 to February 2005, it was found that satisfaction with the quality of life of unemployed residents is lower than that of residents with Aboriginal backgrounds and that satisfaction with the quality of life of the latter is still lower than that of young people. Nevertheless, satisfaction with the quality of life of young people was significantly lower than that of the total sampled population, as well as that of the selected mid-life and retirement groups. Regarding predictors of our three global dependent variables (satisfaction with life as a whole and with the overall quality of life, and happiness) for the three groups (unemployed, Aboriginals and youth) and the total population, we found that the Aboriginal group was most different from all others. Satisfaction with one's own self-esteem was the most influential predictor of each global indicator for every group except Aboriginal residents. For the latter, self-esteem satisfaction was only the strongest predictor of satisfaction with the overall quality of life. The strongest predictor of life satisfaction for the Aboriginal group was satisfaction with friendships, and there were two domain satisfaction scores tied (friendships and living partner) for most influential predictors of happiness. Self-esteem satisfaction ranked second in strength of influence on Aboriginal happiness and life satisfaction.