This article examines how students can use the ePortfolio tool and platform to facilitate and foster increased opportunities for interactions with formal academic advisors and informal mentors. The learning documented within an ePortfolio can be especially useful as a resource for advisors and mentors who are looking not only to connect with their students in meaningful and relevant ways, but who also seek to understand their advisees' backgrounds and interests in order to better guide and support them along their academic journey. Drawing on theories from advising, mentoring, social networking, and communities of practice, the 360° folio networking framework proposed explains the enhanced advising interactions and expanded mentoring opportunities that result when applied to ePortfolios. Examples from several institutions illustrating how ePortfolios have been integrated into advising and mentoring programs are explored.