The discovery of the electron in 1897 deeply impacted the nature of chemistry in the twentieth century. A revolution in the theoretical structure of chemistry as well as in the instrumental tools used in chemical analysis occurred as a result of this discovery. The impact of this revolution on tin oxide chemistry over approximately a 100 year period is the focus of this paper. Important questions addressed include the following: Are tin oxides of importance in our current society or are they only of quaint academic interest? In what way has chemistry as a discipline added to our understanding of the tin oxides and has this added any technological value to these compounds? Does the historical approach followed in this paper offer chemistry educators the opportunity to place current chemical knowledge in a broader epistemological framework? The impact of the answers to these questions on chemistry education is discussed.