This study examined academic staff research productivity in Universities in South-South zone of Nigeria. Ex post facto design was adopted for this study. Three hypotheses were formulated to guide this study. The sample size comprised of 480 academic staff drawn from a population of 3120. Data collection was carried out using a researcher--constructed instrument called Academic Staff Research Productivity Inventory (A.S.R.P.I.), which was validated and pilot tested. The data obtained were treated statistically using Independent t-test and contingency Chi-square (X[squared]) analyses. Results indicated that male and female academic staff differed significantly in their research productivity; married and single academic staff differed significantly in their research productivity and there is a significant influence of areas of specialization on academic staff research productivity. It was recommended that academic staff in universities should be encouraged to carry out research work irrespective of their gender, marital status and areas of specialization. (Contains 3 tables.)