It is of great importance that individuals should become scientifically literate apart from basic education in rapidly integrated world. Until the beginning of 20th century, while development level of countries were determined by literacy rates, today it is thought that one of the basic concepts which would determine development levels will be scientific literacy rate. Individuals should have qualities about scientific literacy in order to adapt to the world, access changing information, participate in discussions which take place in the society, as well as express their view and potential solutions. The aim of this study is to determine scientific literacy level of teacher candidates who have education at two universities (Marmara University and East Mediterranean University), analyze specific variables which have effect on scientific literacy level of teacher candidates through comparative analysis, and make suggestions about education that would be applied in order to improve scientific literacy. This study was designed as a screening model since the aim is to determine scientific literacy level of teacher candidates. Data collection tools included a scientific literacy survey and a variables survey, both developed by researchers. Results reflect that the scientific literacy level of teacher candidates at Marmara University is relatively higher than those in Eastern Mediterranean University.