Purpose: The purpose of this paper is to examine the effects of individually related variables and the moderating role of career strategies on protean career among professionals in Malaysian Electrical & Electronics (E & E) industry. Design/methodology/approach: Research data were gathered from a sample of 306 of professional employees in 18 E & E multinational corporations in Malaysia. Partial least squares structural equation modelling was employed to examine the influences of individually related factors and the moderating role of career strategies on protean career. Findings: The results demonstrate that individually related variables, namely, self-efficacy, outcome expectation, goal orientation and locus of control are viewed as potential predictors of protean career. There are significant moderating effects of career strategies on the relationship between goal orientation and protean career among professional employees. Research limitations/implications: This paper provide an empirical framework to explain protean career based on the review of career-related literatures. Practical implications: The findings provide implications to both individuals and human resource development (HRD) practitioners on new career trends of protean career. Practical interventions are suggested to assist individuals and organizations towards protean career development. Social implications: This paper supports individual protean career development. Originality/value: This paper offers new insight into the predicting factors of protean career and its moderating role on career strategies.