Mobile phones are used around the world, however, there are no definitive rules regarding their appropriate use. In the absence of such codification, the researchers surveyed 225 American and 115 Chinese college students to understand their perceptions of etiquette and appropriate use of mobile phones both in the classroom and in other public places. Several cultural similarities and significant mean differences were found. Similarly, results evince the need for established rules for mobile phone etiquette and the need to implement mobile phones as learning tools in the curriculum.