This study incorporated social media microblogging technology (Twitter) across disciplines to provide 411 first-year undergraduate students studying in large-classroom settings with opportunities to connect in real-time, both within and outside the classroom, with their professor, other students, and members of the professional community. This extension to the traditional teaching and learning environment gave students unique opportunities to enhance their university experience, both from engagement, learning and community-connectedness perspectives. Based on student outcomes and lessons learned, we provide educators with insights into the effective use of social media microblogging technology in a large-classroom format.