The current pilot study examines pre-schooler's play behaviour involving dolls with and without facial characteristics of Down syndrome over a period of 16 weeks. Play behaviours were categorized into one of 3 behavioural categories with predefined observational scoring grids: prosocial, antisocial, or neutral/no behaviour. Participants also…

The Ts65Dn mouse is the best-studied animal model for Down syndrome. In the experiments described here, NMDA-mediated or mGluR-mediated LTD was induced in the CA1 region of hippocampal slices from Ts65Dn and euploid control mice by bath application of 20 [mu]M NMDA for 3 min and 50 [mu]M DHPG for 5 min, respectively. We found that Ts65Dn mice…

The article, "morphosyntactic peculiarities of the speech of children with Down's syndrome", treats, important aspects of the study of two adjacent branches of linguistics, namely, psycholinguistics and neurolinguistics-Language development of the child accompanied by speech disorders, on the other hand, those morphosyntactic features…

This article introduces a set of teaching strategies to enhance second language learning for students with Down syndrome (DS) enrolled in an English course covering material from the first two years of primary school. A set of instructional support strategies has been defined and integrated into an online learning software, developed ad hoc to…

Facial expression processing and the attribution of facial emotions to a context were investigated in adults with Down syndrome (DS) in two experiments. Their performances were compared with those of a child control group matched for receptive vocabulary. The ability to process faces without emotional content was controlled for, and no differences…

Competence in object search and pretend play are argued to reflect young children's representational abilities and appear delayed in children with Down syndrome relative to social and imitative skills. This paper explores the effects on object search and play of this social strength in children with Down syndrome. Three experiments compared…

Many children with Down syndrome demonstrate deficits in phonological awareness, a prerequisite to learning to read in an alphabetic language. The purpose of this study was to determine whether adapting a commercially available phonological awareness program to better align with characteristics associated with the behavioral phenotype of Down…

The results of the experiment demonstrated that Down's syndrome children are equal to non-disabled children matched on mental age, in their ability to discriminate between colors. Both Down's syndrome and non-disabled children made errors of the same kind. Other undifferentiated mentally handicapped children are less consistent in their color…

Background: This study investigated whether a personalized life story book and rummage box enhanced well-being and led to changes in behaviour for people with Down syndrome (DS) who have dementia. Materials and Methods: A randomized single case series design was used with five participants who had DS and a diagnosis of dementia. Participants were…

The brain mechanisms that subserve music recognition remain unclear despite increasing interest in this process. Here we report the results of a magnetoencephalography experiment to determine the temporal dynamics and spatial distribution of brain regions activated during listening to a familiar and unfamiliar instrumental melody in control adults…

Purpose: The aim of this study was to determine when, why, and how the presence of a word's written form during instruction aids vocabulary learning (a process known as "orthographic facilitation"). Method: A systematic review of the research on orthographic facilitation was carried out. PsycInfo, Web of Science, ProQuest, and OpenGrey…

Individuals with Down syndrome tend to have a marked impairment of verbal short-term memory. The chief aim of this study was to investigate whether phonemic discrimination contributes to this deficit. The secondary aim was to investigate whether phonological representations are degraded in verbal short-term memory in people with Down syndrome…

Background: Although there is growing awareness about the potential for people with Down syndrome (DS) to become literate, we know little about the characteristics of handwriting within this population. Methods: Thirty-three participants took part in this experiment. Eleven adults with DS and 22 typically developing individuals (11 children…

Background: The Hebb effect is a form of repetition-driven long-term learning that is thought to provide an analogue for the processes involved in new word learning. Other evidence suggests that verbal short-term memory also constrains now vocabulary acquisition, but if the Hebb effect is independent of short-term memory, then it may be possible…

This meta-analysis combines the effect size (ES) of 40 explicit memory experiments in populations with intellectual disability (ID). Eight meta-analyses were performed, as well as contrast tests between ES. The explicit memory of participants with ID was inferior to that of participants with typical development (TD). Relatively preserved explicit…