It has been estimated that 1 in 4 persons will experience a depressive episode over his or her lifetime (G. Gintner, 2001). The author discusses various etiologies of depression, interpersonal factors related to depression, and research on various communication-focused counseling interventions. The author maintains that published literature supports a communication-skills-centered approach to alleviating the symptoms of depression and recommends that professional counselors assert their ability to provide their clients with effective and healthy treatment for depression.