This article summarizes the results of a qualitative study of career transition experiences of middle-aged male scientists and engineers in the current socioeconomic environment in the United States. The study addresses the effects of the transitions from psychosocial perspectives. The authors selected participants from research organizations, industry, and academic fields. The authors used a narrative approach to collect data and analyzed the data using a grounded theory approach. The results suggest that the major factors that describe the dynamics in the career transition experiences are personhood, relationships, lifestyle, and workplace environment. The findings and their implications in developing coping skills and counseling strategies are discussed.