A multifaceted experiment, accessible to students either in an introductory organic chemistry course or in a more advanced laboratory setting, is described for investigating the addition of dichlorocarbene to E- and Z-[beta]-methylstyrenes. The innovative exercise, which integrates elements of synthesis, mechanisms, instrumental analysis,…

This advanced undergraduate chemistry laboratory exercise takes advantage of the unique spectroscopic properties of the free radical chlorine dioxide to allow for a direct comparison of its symmetric stretch in both the ground and excited states. It incorporates several subject areas covered in an undergraduate chemistry degree (synthesis,…

The Distributed Drug Discovery (D3) program trains students in three drug discovery disciplines (synthesis, computational analysis, and biological screening) while addressing the important challenge of discovering drug leads for neglected diseases. This article focuses on implementation of the synthesis component in the second-semester…

Robots that can learn new behaviors. Robots that can reproduce themselves. Science fiction? Not anymore. Roboticists at Cornell's Computational Synthesis Lab have developed just such engineered creatures that offer interesting implications for education. The team, headed by Hod Lipson, was intrigued by the question, "How can you get robots to be…

Computational chemistry techniques are used along with spectroscopy to characterize acetaminophen synthesized in an undergraduate chemistry laboratory experiment. The inclusion of electronic structure calculations to provide infrared and Raman spectra in the synthesis and characterization of acetaminophen connects over-the-counter medications with…

Background: Collaboration has commonly been integrated in computational thinking education to foster novice learning. While the majority of existing studies on developing students' CT skills have been based on competency or personality factors, social factors have been largely ignored. Objectives: This systematic review, framed by social cognitive…

This paper explores three simple data manipulation techniques (synthesis, augmentation, curriculum) for improving abstractive summarization models without the need for any additional data. We introduce a method of data synthesis with paraphrasing, a data augmentation technique with sample mixing, and curriculum learning with two new difficulty…

Memory consolidation and reconsolidation require kinase activation and protein synthesis. Blocking either process during or shortly after training or recall disrupts memory stabilization, which suggests the existence of a critical time window during which these processes are necessary. Using a computational model of kinase synthesis and…

Background: Computational thinking (CT) is regarded as an essential 21st-century skill, and attempts have been made to integrate it into other subjects. Instructional approaches to CT development and assessment in the field of computer science have attracted global attention, but the influence of CT skills on other subject areas is…

The study aims to present how to apply a STEM activity in which physical computing principles and computational thinking processes are used as a differentiation practice to be used in the education of gifted students. In the activity, the students designed smart packaging that will provide healthy long-term storage of foods to solve the greenhouse…

This paper aims at exploring students' experiences when engaging in mathematical problem-solving through computational thinking and programming by a combination of theoretically derived insights and task-based activities. The main method used is a semi-structured interview with two undergraduate students who were presented with a mathematical task…

Brief experimental analysis (BEA) is a quick method used to identify the function of student learning difficulties and match effective interventions to students' needs. Extensive work has been done to explore the use of this methodology to determine effective reading interventions; however, a smaller number of published studies have examined the…

A laboratory project to introduce upper-level undergraduates to Pd-catalyzed C-N [sigma]-bond forming reactions is described. The exercise involves evaluation of monodentate phosphine ligands and solvents for the Buchwald-Hartwig coupling of 4-chloro-or 4-bromo-anisole with morpholine. Students gain experience in the synthesis of a biarylphosphine…

As a cross-cutting and comprehensive subject, medicinal chemistry involves the knowledge of chemical, biological, medical, and pharmaceutical sciences. A comprehensive medicinal chemistry experience for undergraduates is expected to train various experimental skills and enhance their scientific research ability. Herein, a series of laboratory and…

Background and Context: We explored how learning trajectories (LTs) might be used to design variables instruction. Objective: We aimed to develop an LT for variables and use it to guide curriculum development for fourth graders working in Scratch in an integrated mathematics+CS curriculum. Method: We synthesized learning goals (LGs) and levels of…