The present study examined the reliability and validity of the Greek version of the Task-Specific Occupational Self-Efficacy Scale in a sample of 170 high school students. Drawing on current social cognitive career theory, the validity of the TSOSS is supported by the expected gender differences on the TSOSS factors, and their high correlations with Self-Directed Search summary scores, and vocational choice goals. Additionally, there seems to be some evidence that self-efficacy beliefs, as measured by the TSOSS, may affect choice goals both directly and indirectly. The empirical structure of the instrument examined by a cluster analysis algorithm was perfectly confirmed, and its stability is supported by adequate test-retest correlations and high internal consistency coefficients. On the basis of these findings a preliminary evaluation of the TSOSS is made when used with a Greek sample. Implications for research and career guidance are discussed.