This graduate-level DNA methods laboratory course is designed to model a discovery-based research project and engages students in both traditional DNA analysis methods and modern recombinant DNA cloning techniques. In the first part of the course, students clone the "Drosophila" ortholog of a human disease gene of their choosing using…

The work described in this report is the first phase of a project to provide easy-to-use tools for authoring and rendering secondary-school algebra-level math expressions in synthesized speech that is useful for students with blindness or low vision. This report describes the initial development, software implementation, and evaluation of the…

A nine-week laboratory project designed for a sophomore level molecular biology course is described. Small groups of students (3-4 per group) choose a tumor suppressor gene (TSG) or an oncogene for this project. Each group researches the role of their TSG/oncogene from primary literature articles and uses bioinformatics engines to find the gene…

This essay raises concerns over the future direction for educational aid designed to promote literacy in developing countries. The essay focuses on the EGRA (Early Grade Reading Assessment) initiative in Africa. At one level, this essay challenges the claims for empirical and research-based support for the EGRA. At a broader level, this essay…

This report profiles Sciotoville Elementary Academy (SEA), a unique Ohio charter school that draws kids and families from Appalachian Ohio. SEA is one of the few charters located outside of the state's urban communities. This school's accomplishments illustrate what's possible within charter schooling for educators, families, and an entire…

The genes responsible for luminescence in various species of the marine microorganism "Photobacterium", have been used for many years as a tool by researchers and instructors. In particular, the "lux" operon of "Photobacterium fischeri" has been used by many instructors to teach recombinant DNA techniques. Two methods using an automated plate…

Plants defend themselves against pathogens via the expressions of disease resistance (R) genes. Many plant R gene products contain the characteristic nucleotide-binding site (NBS) and leucine-rich repeat (LRR) domains. There are highly conserved motifs within the NBS domain which could be targeted for polymerase chain reaction (PCR) cloning of R…

This essay examines the theme and trope of "copies" in Kazuo Ishiguro's novel "Never Let Me Go." Whatever one's final reading of the novel, the theme and thread of copy, copies, copying and copied is never far off. In a semantic sense then, the act of "copying", both as a verb and the indexing of "copies" as…

The promise of science is that its methods cause others to believe its results. This foundation is served by trust, accuracy, and transparency. Unfortunately, current research practices in psychology are known to often produce inaccurate, irreproducible, and imprecise results. "Toward a More Perfect Psychology" introduces a plethora of…

We describe the development of a mini-library of human DNA fragments for use in an enquiry-based learning (EBL) undergraduate practical incorporating "wet-lab" and bioinformatics tasks. In spite of the widespread emergence of the polymerase chain reaction (PCR), the cloning and analysis of DNA fragments in "Escherichia coli"…

The number of university rankings systems in use around the world has increased dramatically over the last decade. As they have spread, they have mutated; no longer are ranking systems simply clones of the original ranking systems such as "US News" and "World Report". A number of different types of "mutation" have occurred, so that there are now…

Humic substances (HS) are the humified portions of totally decomposed soil organic matter that are ubiquitous in nature. Although these substances have been studied for more than 200 years, neither their metabolic capabilities nor a specific chemical structure has yet to be determined. HS have been studied as a carbon source in many environments…

Everyone tells tales about advisers. Some of the stories are heartwarming, while others are prurient, even horrifying. Most everyone has such stories on tap because the adviser-student relationship is the most crucial in turning a graduate student into a professional. the ties between graduate students and advisers are both professional and…

Children learn a whole raft of skills in the first seven or eight years of life by closely imitating their parents and teachers. But for children to grow up as clones at a time of rapid cultural and economic environmental change would be nothing short of disastrous. We now know that children need the struggle of adolescence to put away those…

The U.S. Food and Drug Administration (FDA) announced recently that food products derived from some animal clones and their offspring are safe for human consumption. In response to criticism that it had failed to engage with ethical, social, and economic concerns raised by livestock cloning, the FDA argued that addressing normative issues prior to…