Studies indicate that the use of technologies as teaching aids and tools for self-study is influenced by students' attitudes toward computers and their applications. The purpose of this study is to determine whether taking a Computer Literacy and Applications (CLA) course has an impact on students' attitudes toward computer applications, across various undergraduate disciplines. A Computer Application Attitude (CAA) questionnaire was administered at the beginning and at the end of the semester to social science students enrolled in a CLA course. The study population was divided into two groups according to the students' field of study: quantitative-oriented and qualitative-oriented. A significant difference was found in attitudes before and after the CLA course only in the quantitative group. Based upon the results of this study, it is recommended to offer different computer literacy courses to the different groups to improve students' attitudes toward the use of these applications. (Contains 5 tables.)