ERIC Number: EJ941052
Record Type: Journal
Publication Date: 2011-Aug
Pages: 3
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-0021-9584
EISSN: N/A
GC-MS Quantitation and Identification of Bisphenol-A Isolated from Water
Mead, Ralph N.; Seaton, Pamela J.
Journal of Chemical Education, v88 n8 p1130-1132 Aug 2011
Isolation and identification of organic compounds is a necessary skill chemistry students must be able to do with proficiency. In this upper-level undergraduate laboratory, students isolate bisphenol-A (BPA; 4-4'-isopropylidenediphenol) from water using solid-phase extraction (SPE) followed by derivatization with analysis by GC-MS. The students learn the proper steps and techniques of SPE that include conditioning, equilibration, washing, and eluting. The students are then asked to identify the BPA peak from the GC-MS analysis of a mixture of standards based upon the molecular ion, keeping in mind the change in molecular weight upon derivatization. Interpretation of GC-MS data showed predictable fragmentation and highlights the formation of benzylic carbocations. Quantification was done by an external calibration curve and the sample was quantified and a percent recovery is calculated. (Contains 3 figures.)
Descriptors: College Science, Science Instruction, Water, Scientific Principles, Undergraduate Study, Science Process Skills, Science Laboratories, Molecular Structure, Organic Chemistry
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A