There is a deficit of male and female students entering the fields of math and science, and the need for highly educated individuals in these areas is expected to increase. While various factors may play a role in creating this deficit, there is a lack of research on one factor, that of student attitudes toward science. The theories of social aspects, how children learn and how teachers teach provided the framework for an examination of public school student attitudes toward science. The purpose of this study was to determine if there is a significant difference in attitudes toward science in Grades 4-12 based on gender and grade level. Using a quantitative one-shot case study preexperimental design, the study described the relationships in student attitudes toward science and how those relationships change with grade and gender. This study investigated the relationship in attitudes toward science in different grade levels, the relationship in male and female attitudes toward science in different grade levels, and the difference in attitudes toward science between male and female students. The Kruskal-Wallis test and the nonparametric independent samples test for gender differences were performed to examine grade level, gender, and attitudes toward science. The convenience sample of 1,008 students was drawn from a population of approximately 1,200 students enrolled in Grades 4 through 12 in a rural, public school district in the northeastern United States. The data analysis revealed no difference in male attitudes toward science, but did reveal a significant difference in female attitudes toward science between different grade levels, (H(8) = 32.773, p less than 0.000). Implications for social change include an improved student attitude toward science, which increases educational opportunities and career options for underrepresented groups. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com/en-US/products/dissertations/individuals.shtml.]