ERIC Number: EJ805554
Record Type: Journal
Publication Date: 2008-Aug
Pages: 6
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-1072-0502
EISSN: N/A
Reactivation-Dependent Amnesia in Pavlovian Approach and Instrumental Transfer
Lee, Jonathan L. C.; Everitt, Barry J.
Learning & Memory, v15 n8 p597-602 Aug 2008
The theory of memory reconsolidation relates to the hypothesized restabilisation process that occurs following the reactivation of a memory through retrieval. Thus, the demonstration of reactivation-dependent amnesia for a previously acquired memory is a prerequisite for showing that such a memory undergoes reconsolidation. Here, we show that the appetitive Pavlovian representations that underlie Pavlovian approach and Pavlovian-instrumental transfer are destabilized following their retrieval. This reactivation-dependent amnesia demonstrates that the general motivational or incentive properties of appetitive conditioned stimuli, as well as their conditioned reinforcing properties, can be reduced by blocking memory reconsolidation.
Descriptors: Classical Conditioning, Recall (Psychology), Retention (Psychology), Learning Processes, Neuropsychology
Cold Spring Harbor Laboratory Press. 500 Sunnyside Boulevard, Woodbury, NY 11797-2924. Tel: 800-843-4388; Tel: 516-367-8800; Fax: 516-422-4097; e-mail: cshpres@cshl.edu; Web site: http://www.learnmem.org/
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A